Born Vera Buchthal in the German city of Dortmund in 1933, Dame Stephanie was one of thousands of Jewish children to flee the Nazis to Britain as part of the Kindertransport.

She went on to become a computer industry and women’s rights pioneer in the 1950s and 1960s, and founded the software company Freelance Programmers.

The firm almost exclusively hired women, whilst she adopted the name “Steve” to help her in the male-dominated tech world.

In later life, Dame Stephanie donated most of her £150m fortune to good causes, including to help those with autism and to IT projects.

Joe Robinson, from Dreweatts, said the collection was “defined by clarity of taste and the confidence to live with exceptional works”.

From modern sculpture and studio pottery to beautifully chosen furnishings, every piece reflects Dame Stephanie’s belief that art belongs in daily life.

He added that the sale felt like a “fitting tribute to such a significant personal legacy“.

Autistica’s interim chief executive Rebecca Sterry said the charity was “honoured” that it would benefit from funds raised by the auction.

Dame Stephanie Shirley’s life was defined by purpose, curiosity, and generosity,” she said.

Her values and beliefs are embedded in our charity and drive our commitment to innovative problem solving, acting with urgency and embracing difference.

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